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In vivo priming of HIV-specific CTLs determines selective cross-reactive immune responses against poorly immunogenic HIV-natural variants Boissonnas, A., et al.
Journal of Immunology
169 (7): 3694-3699 OCT 1 2002
Link Degeneracy of the TCR repertoire might allow for cross-recognition of epitope variants. However, it is unclear how the first encounter with HIV Ags determines recognition of emerging epitope variants. This question remains crucial in the choice of HIV vaccine sequences given the virus variability.
—Posted: October 25, 2002
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