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Vol. 2, No. 17, 23 August 2002
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Other Issues:
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AIDScience Perspective:
With several products moving into late-stage clinical trials (and one phase III trial already completed), the microbicides field is accumulating valuable experience working with women at high risk for HIV—experience that also offers important lessons for vaccines:
Learning from microbicides: A young field's experience working with high-risk women
by Emily Bass, from the IAVI Report.
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Hot News:
A new vaccine candidate generated neutralizing antibodies that are not type-specific. Structures consisting of covalently crosslinked complexes of soluble human CD4 (shCD4) and HIV-1IIIB envelope glycoproteins (gp120 or gp140) were able to generate antibodies in rhesus macaques that neutralized a wide range of primary HIV-1 isolates regardless of the coreceptor usage or genetic subtype.
Proc. Natl. Acad. Sci. USA, published online before print August 21, 2002 [Read abstract]
Commentary about the paper in the Institute of Human Virology's Web site [Go to site]
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Unrecognized HIV infection, risk behaviors, and perceptions of risk among young black men who have sex with men (BMSM). Data from the CDC's Young Men's Survey (YMS) were used to evaluate the prevalence of unrecognized HIV infection, barriers to testing, and reasons for nonuse of condoms among BMSM aged 15-22 years. The findings in this report are consistent with previous studies suggesting that in several U.S. cities, the majority of young HIV-infected MSM, particularly BMSM, were unaware of their infection.
Morbidity and Mortality Weekly Report 51(33), 733, 23 August 2002 [Read report]
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HIV prevention research: Cumulative knowledge or accumulating studies? The U.S. CDC HIV/AIDS Prevention Research Synthesis (PRS) project found over 4000 studies related to the prevention of HIV infection. The Journal of Acquired Immune Deficiency Syndromes has published a supplement comprising articles from the PRS project. The project claims to be the largest research review conducted to date of the effectiveness of interventions to reduce HIV risk behavior.
Journal of Acquired Immune Deficiency Syndromes 30(Supplement 1), 1 July 2002 [Go to journal]
Or, go to Journal Headlines to click on individual article links:
[This month's Journal Headlines]
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Latest News Headlines:
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African AIDS activists unite. Newsday. August 23, 2002
| Researchers publish findings on HIV targeting. Yahoo! News. August 23, 2002
| AIDS pandemic stunts southern African growth. Financial Times. August 22, 2002
| New AIDS drug raises hopes, fears. Newsday. August 22, 2002
| Activists angry as poor still succumb to disease. Philadelphia Inquirer. August 22, 2002
| Vietnam begins production of lower-priced AIDS drug. Yahoo! News. August 22, 2002
| Chimps may have survived HIV epidemic. Yahoo! News. August 22, 2002
| Finding of high number of HIV cases among prison inmates unsettles Lithuania. Yahoo! News. August 22, 2002
| Politics and AIDS (editorial). San Francisco Chronicle. August 20, 2002
| New potential drugs for AIDS discovered. Yahoo! News. August 20, 2002
| AIDS drugs: 'There is no alternative'. BBC News. August 20, 2002
| New approach to AIDS vaccine shows hope in monkeys. Yahoo! News. August 20, 2002
| At International HIV/AIDS Conference, daunting challenges mixed with hope. JAMA News. August 19, 2002
| AIDS protest fuels audit request. MSNBC. August 19, 2002
| Youth ignorance of HIV/AIDS. JAMA News. August 19, 2002
| 'HIV test for African nurses' opposed. BBC News. August 18, 2002
| AIDS waste (editorial). Washington Times. August 17, 2002
| China to get cheaper AIDS drug. BBC News. August 16, 2002
| AIDS official dubs CDC scrutiny a 'witch hunt'. Washington Times. August 16, 2002
| South Africa soaks up pressure to change HIV/AIDS policy. Lancet News. August 15, 2002
| AIDS hits poor, women harder in New York. Newsday. August 15, 2002
| Report: AIDS cases on the rise in New York. Newsday. August 15, 2002
| Kenya expands AIDS control program for mothers. Yahoo! News. August 15, 2002
| HIV infection rates soaring in Swaziland. Yahoo! News. August 15, 2002
| Immune Response announces results from trial with REMUNE. Immune Response Corp. release. August 15, 2002
| Men unwilling to negotiate female condom use. AllAfrica.com. August 14, 2002
| Nairobi has 1.1 million HIV/Aids orphans. AllAfrica.com. August 14, 2002
| New tactic to prevent AIDS spread. New York Times. August 13, 2002
| AIDS group's graphic tactics scrutinized—Federal team questions staff. San Francisco Chronicle. August 13, 2002
| Cheaper HIV-AIDS drugs to improve treatment for patients in Bahamas. Yahoo! News. August 13, 2002
| Many teens still can't tell HIV fact from fiction. Yahoo! News. August 13, 2002
| The future of HIV drugs. BBC News. August 13, 2002
| Examining Merck's health. Philadelphia Inquirer. August 13, 2002
| De Beers becomes latest company to make AIDS drugs available to its employees. Yahoo! News. August 12, 2002
| HIV/AIDS will be the crucial test of African leadership. AllAfrica.com. August 12, 2002
| AIDS research has improved patients' quality of life. Miami Herald. August 10, 2002
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More news headlines: This week | Last week | Search archive |
Latest Journal Headlines:
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| Disulfide exchange in domain 2 of CD4 is required for entry of HIV-I. Nature Immunology. (Posted: August 19, 2002) | | NeuroAIDS: AIDS dementia. Medical Clinics of North America. (Posted: August 19, 2002) | | HIV-1 therapeutic vaccines. Journal of Infection. (Posted: August 19, 2002) | | Semi-allogeneic vaccines for patients with cancer and AIDS. Journal of Immunotherapy. (Posted: August 19, 2002) | | Cross-clade HIV-1-specific neutralizing IgA from HIV-1-exposed, persistently seronegative subjects. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 19, 2002) | | HIV risk in a Mexican migrant community. American Journal of Public Health. (Posted: August 19, 2002) | | SIVmac pathogenesis in rhesus macaques of Chinese and Indian origin. AIDS. (Posted: August 19, 2002) | | Sexual risk behaviors and implications for secondary HIV transmission. AIDS. (Posted: August 19, 2002) | | High-risk sexual behaviour increases among London gay men between 1998 and 2001. AIDS. (Posted: August 19, 2002) | | The HIV-1 vaccine race. Cell. (Posted: August 19, 2002) | | Intranasal immunization protects against intravaginal challenge. Virology. (Posted: August 19, 2002) | | Dendritic cell amplification of HIV type 1-specific CD8(+) T cell responses in seronegative women. AIDS Research and Human Retroviruses. (Posted: August 15, 2002) | | Theoretical issues in the synthesis of HIV prevention research. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | The HIV/AIDS Prevention Research Synthesis Project. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | A profile of U.S.-based trials of behavioral and social interventions for HIV risk reduction. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | Acquisition and review of non-U.S.-based HIV risk reduction intervention studies. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | The Cochrane Collaborative Review Group on HIV Infection and AIDS. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | A protocol for the analytical aspects of a systematic review of HIV prevention research. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | A meta-analysis of the effect of HIV prevention interventions on the sex behaviors of drug users. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | Meta-analysis of the effects of behavioral HIV prevention interventions on adolescents. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | Review and meta-analysis of HIV prevention intervention research for heterosexual adults. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | HIV prevention research for men who have sex with men: a systematic review and meta-analysis. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | The HIV/AIDS Prevention Research Synthesis Project: implications for federal HIV prevention policy. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | Implications of the HIV/AIDS Prevention Research Synthesis Project on health departments. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | HIV prevention research: Cumulative knowledge or accumulating studies?. Journal of Acquired Immune Deficiency Syndromes. (Posted: August 15, 2002) | | A Tat subunit vaccine confers protective immunity in mice. Proc. Natl. Acad. Sci. USA. (Posted: August 15, 2002) |
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